Intestinal Organoids for Modelling Intestinal Development and Disease
The client: Dr Nicholas Hannan
The brief: To produce a series of three figures to accompany a review of intestinal organoids, published in the Royal Society's journal Philosophical Transactions B. The figures demonstrated the different tissues present in both the small and large intestine; detailed the factors introduced to an intestinal stem cell to maintain it's multipotency or stemness and how this is measured; and the methods which could be used to harvest stem cells and grow intestinal organoids.
The outcome: Each figure was carefully researched, sketched, and finally hand drawn using ink. The individual elements were scanned, coloured and composited digitally, so that a vibrant colour palette could be used to easily identify the individual cell types.